| Identification | Back Directory | [Name]
ICI 186756 | [CAS]
95500-67-7 | [Synonyms]
ICI 186756
4-[[(2S)-1-[[(2S)-3-methyl-1-[[(2S)-1-[(2S)-3-methyl-1-oxobutan-2-yl]pyrrolidine-2-carbonyl]amino]-1-oxobutan-2-yl]amino]-1-oxo-6-(phenylmethoxycarbonylamino)hexan-2-yl]amino]-4-oxobutanoic acid | [Molecular Formula]
C33H49N5O9 | [MOL File]
95500-67-7.mol | [Molecular Weight]
659.77 |
| Hazard Information | Back Directory | [Description]
Ici 186756 is a novel, potent, and selective inhibitor of human neutrophil elastase. | [Uses]
ICI 186756 is a compound that inhibits the activity of human neutrophil elastase, has a competitive inhibitory effect on the enzyme, can inhibit enzyme-induced lung changes, and can also modulate hamster lung lesions. | [References]
[1] Biochemical and pharmacological characterization of ICI 186,756: a novel, potent, and selective inhibitor of human neutrophil elastase |
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