| Identification | Back Directory | [Name]
Elziverine | [CAS]
95520-81-3 | [Synonyms]
Elziverine
1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-4-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]isoquinoline
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]isoquinoline
Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-4-[[4-(2-methoxyphenyl)-1-piperazinyl]methyl]- | [Molecular Formula]
C32H37N3O5 | [MOL File]
95520-81-3.mol | [Molecular Weight]
543.65 |
| Hazard Information | Back Directory | [Uses]
Elziverine (Ro 22-4839) is a brain circulation improvement agent with vasospasm antispasmodic effects. Elziverine is a calmodulin antagonist. Elziverine inhibits erythrocyte cell membrane rupture, platelet aggregation and lipid peroxidation[1]. | [References]
[1] Nakajima T, et al. Calmodulin antagonistic action of the cerebral circulation improver 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-4- ([4-(2-methoxyphenyl)-1-piperazinyl]methyl)isoquinoline. Arzneimittelforschung. 1987 Jun;37(6):674-9. PMID:2822056 |
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