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955371-66-1

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955371-66-1 Structure

955371-66-1 Structure
IdentificationBack Directory
[Name]

VK-II-36
[CAS]

955371-66-1
[Synonyms]

VK-II-36
6-(9H-carbazol-4-yloxymethyl)-4-[2-(2-methoxyphenoxy)ethyl]morpholin-3-one
3-Morpholinone, 6-[(9H-carbazol-4-yloxy)methyl]-4-[2-(2-methoxyphenoxy)ethyl]-
[Molecular Formula]

C26H26N2O5
[MOL File]

955371-66-1.mol
[Molecular Weight]

446.49
Chemical PropertiesBack Directory
[Boiling point ]

698.6±55.0 °C(Predicted)
[density ]

1.271±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

16.54±0.30(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

VK-II-36 is a carvedilol analog that suppresses sarcoplasmic reticulum Ca2+release but does not block the β-receptor.VK-II-36 inhibits triggered activities evoked by both early and delayed after depolarizations[1].
[References]

[1] Maruyama M, et al. Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations. Heart Rhythm. 2013 Jan;10(1):101-7. DOI:10.1016/j.hrthm.2012.09.006
Spectrum DetailBack Directory
[Spectrum Detail]

VK-II-36(955371-66-1)1HNMR
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