| Identification | Back Directory | [Name]
momordin II | [CAS]
95851-41-5 | [Synonyms]
momordin II
3-O-<α-L-arabinopyranosyl (1->3)-β-D-glucuronopyranosyl>-oleanolic acid β-D-glucopyranosyl (1->28) ester | [Molecular Formula]
C47H74O18 | [MOL File]
95851-41-5.mol | [Molecular Weight]
927.09 |
| Hazard Information | Back Directory | [Uses]
Momordin II, an oleanane-type triterpene glycoside, is a ribosome inactivating protein. Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity[1][2][3]. | [References]
[1] M Ortigao, et al. Momordin II, a ribosome inactivating protein from Momordica balsamina, is homologous to other plant proteins. Nucleic Acids Res DOI:10.1093/nar/20.17.4662
[2] P Valbonesi, et al. Preparation of highly purified momordin II without ribonuclease activity. Life Sci. 1999;65(14):1485-91. DOI:10.1016/s0024-3205(99)00389-6
[3] Hung-Tse Huang, et al. Anti-Inflammatory and anti-proliferative oleanane-type triterpene glycosides from the vine of Momordica cochinchinensis. Nat Prod Res. 2021 Aug;35(16):2707-2714. DOI:10.1080/14786419.2019.1666383 |
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