ChemicalBook--->CAS DataBase List--->958647-10-4

958647-10-4

958647-10-4 Structure

958647-10-4 Structure
IdentificationBack Directory
[Name]

Flutianil
[CAS]

958647-10-4
[Synonyms]

OK 5203
V 10118
Flutianil
(2Z)-2-[[2-Fluoro-5-(trifluoromethyl)phenyl]thio]-2-[3-(2-methoxyphenyl)-2-thiazolidinylidene]acetonitrile
Acetonitrile, 2-[[2-fluoro-5-(trifluoromethyl)phenyl]thio]-2-[3-(2-methoxyphenyl)-2-thiazolidinylidene]-, (2Z)-
(2Z)-2-[2-fluoro-5-(trifluoromethyl)phenyl]sulfanyl-2-[3-(2-methoxyphenyl)-1,3-thiazolidin-2-ylidene]acetonitrile
[Molecular Formula]

C19H14F4N2OS2
[MDL Number]

MFCD28009633
[MOL File]

958647-10-4.mol
[Molecular Weight]

426.45
Chemical PropertiesBack Directory
[Boiling point ]

457.6±45.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[pka]

-1.86±0.20(Predicted)
[Henry's Law Constant]

7.2×101 mol/(m3Pa) at 25℃, Ebert et al. (2023)
[EPA Substance Registry System]

Flutianil (958647-10-4)
Safety DataBack Directory
[Symbol(GHS) ]

Environment (GHS09)
GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P391-P501
Hazard InformationBack Directory
[Description]

Flutianil is a horticultural fungicide. It has a very low solubility and is volatile. It is persistent in soils. It has a low mammalian toxicity but there are some concerns regarding effects on reproduction. It exhibits moderate to low toxicity to most aquatic and terrestrial organisms.
[Chemical Properties]

Odorless, white crystalline powder. Boiling point (2.53 kPa) 299.1°C. Vapor pressure (25°C) <1.3×10-2 mPa. KowlogP = 2.9. Relative density (30°C) 1.45. Solubility in water 0.0079 mg/L (20°C). Stable when heated to 280°C. No hydrolysis occurs at 50°C and pH = 4, 7, or 9. Photodecomposition DT50 in aqueous solution 3-4 days.
[Uses]

Flutianil is a fungicide used in the treatment and protection of crops.
[Definition]

ChEBI: A member of the class of thiazolidines that is N-(o-methoxyphenyl)thiazolidine which is substituted at position 2 by a methylene group, the hydrogens of which are replaced by cyano and [2-fluoro-5-(trifluoromethyl)phenyl]sul anediyl groups; the double bond conjugated to the cyano group has Z configuration. A fungicide intended for use on horticultural crops including strawberries and grapevines.
[Production Methods]

Flutianil is produced commercially through a multi-step synthesis centred on thiazolidine chemistry, where an o methoxyphenyl thiazolidine core is functionalised with cyano and fluorinated arylthio substituents. Industrial production begins with the preparation of the thiazolidine scaffold, followed by introduction of the 2 fluoro 5 trifluoromethylphenylthio group via selective sulfanyl substitution. The key intermediate is then condensed with acetonitrile derivatives to install the cyano functionality, ensuring the final (Z) configuration of the double bond. Careful control of reaction conditions is required to achieve the correct stereochemistry and high yield. The crude product undergoes purification steps such as solvent extraction and recrystallisation to reach technical-grade purity.
[Mechanism of action]

Contact action - both fungitoxic and fungistatic
[Pesticide Type]

Fungicide
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