| Identification | Back Directory | [Name]
N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide | [CAS]
959610-24-3 | [Synonyms]
MiristoylTetrapeptide-12
N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide
L-Alaninamide, N2-(1-oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-
N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]tetradecanamide | [EINECS(EC#)]
205-358-3 | [Molecular Formula]
C32H63N7O5 | [MDL Number]
MFCD30749830 | [MOL File]
959610-24-3.mol | [Molecular Weight]
625.89 |
| Chemical Properties | Back Directory | [Boiling point ]
932.2±65.0 °C(Predicted) | [density ]
1.060±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
13.43±0.46(Predicted) | [Sequence]
{Myristoyl-Lys}-Ala-Lys-Ala-NH2 | [InChIKey]
GGEXWRGHXPPRBY-FWEHEUNISA-N | [SMILES]
C(N)(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCC |
| Hazard Information | Back Directory | [Uses]
Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes[1][2]. | [References]
[1] Haeyoung Kwon, et al. Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide. Cell Biochem Funct. 2014 Dec;32(8):665-74. DOI:10.1002/cbf.3070
[2] C. Diehl. Peptides in cosmeceuticals. ISSN 1727-5741 (Print), ISSN 2522-1035 (Online). |
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