| Identification | Back Directory | [Name]
OTAVA-BB 7070707032 | [CAS]
959626-45-0 | [Synonyms]
OTAVA-BB 7070707032
cFMS Receptor Inhibitor IV
5-cyano-N-[2,5-di(piperidin-1-yl)phenyl]furan-2-carboxamide | [Molecular Formula]
C22H26N4O2 | [MDL Number]
MFCD10568148 | [MOL File]
959626-45-0.mol | [Molecular Weight]
378.47 |
| Chemical Properties | Back Directory | [Boiling point ]
530.5±50.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 31.25 mg/mL (82.57 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
10.55±0.70(Predicted) | [color ]
Light yellow to yellow | [InChI]
1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27) | [InChIKey]
FQGXFVDABCBEFW-UHFFFAOYSA-N | [SMILES]
N4(CCCCC4)c1c(cc(cc1)N3CCCCC3)NC(=O)c2[o]c(cc2)C#N |
| Hazard Information | Back Directory | [Uses]
cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM[1]. | [storage]
Store at -20°C | [References]
[1] Patch RJ, et al. Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6070-4. DOI:10.1016/j.bmcl.2007.09.057 |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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