ChemicalBook--->CAS DataBase List--->959746-77-1

959746-77-1

959746-77-1 Structure

959746-77-1 Structure
IdentificationBack Directory
[Name]

CyclopropanecarboxaMide, N-[3-(2-Methoxyethyl)-4,5-diMethyl-2(3H)-thiazolylidene]-2,2,3,3-tetraMethyl-, [N(Z)]-
[CAS]

959746-77-1
[Synonyms]

A-836339 (A836339)
A-836339,A 836339,Cannabinoid Receptor,A836339,inhibit,Inhibitor
1-(tetrahydropyran-4-ylMethyl)-1H-indol-3-yl]-(2,2,3,5-tetraMethylcyclopropyl)Methanone
CyclopropanecarboxaMide, N-[3-(2-Methoxyethyl)-4,5-diMethyl-2(3H)-thiazolylidene]-2,2,3,3-tetraMethyl-, [N(Z)]-
[Molecular Formula]

C16H26N2O2S
[MDL Number]

MFCD17167006
[MOL File]

959746-77-1.mol
[Molecular Weight]

310.46
Chemical PropertiesBack Directory
[Boiling point ]

388.4±44.0 °C(Predicted)
[density ]

1.14±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml; Methanol: 1 mg/ml
[form ]

A crystalline solid
[pka]

-3.95±0.60(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

A-836339 is a synthetic cannabinoid (CB) which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice. At higher doses, A-836339 also decreases spontaneous locomotor activities, consistent with CB1 activation. This product is intended for forensic and research applications.
[Uses]

A-836339, is a cannabinoid CB2 receptor-selective agonist; exhibits high potencies at CB(2) and selectivity over CB(1) receptors. Synthetic Cannabinoids.
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