| Identification | Back Directory | [Name]
8-Benzyloxy-2'-deoxy-D-guanosine | [CAS]
96964-90-8 | [Synonyms]
8-Benzyloxy-2’-deoxyguanosine
8-Benzyloxy-2a€-deoxyguanosine
8-Benzyloxy-2'-deoxy-D-guanosine
2'-Deoxy-8-(phenylMethoxy)guanosine
Guanosine, 2'-deoxy-8-(phenylmethoxy)-
2-amino-9-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-3H-purin-6-one | [Molecular Formula]
C17H19N5O5 | [MDL Number]
MFCD03701133 | [MOL File]
96964-90-8.mol | [Molecular Weight]
373.36 |
| Chemical Properties | Back Directory | [Melting point ]
175-177°C | [density ]
1.70±0.1 g/cm3(Predicted) | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
solid | [pka]
9.30±0.20(Predicted) | [color ]
Pale Beige to Brown |
| Hazard Information | Back Directory | [Chemical Properties]
Brown solid | [Uses]
2′-Deoxy-8-(phenylmethoxy)guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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