ChemicalBook--->CAS DataBase List--->97145-43-2

97145-43-2

97145-43-2 Structure

97145-43-2 Structure
IdentificationBack Directory
[Name]

KKI 5
[CAS]

97145-43-2
[Synonyms]

1G,10G,100G
L-Glutamamide, 1-acetyl-L-prolyl-L-phenylalanyl-L-arginyl-L-seryl-L-valyl- (9CI)
[Molecular Formula]

C35H55N11O9
[MOL File]

97145-43-2.mol
[Molecular Weight]

773.88
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

12.94±0.46(Predicted)
[Water Solubility ]

Soluble in water at 1mg/ml
[Sequence]

Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2
Hazard InformationBack Directory
[Uses]

KKI-5 is a specific inhibitor of tissue kallikrein. KKI-5 can attenuate breast cancer cell invasion[1].
[References]

[1] Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102. DOI:10.1021/jm00095a002
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