| Identification | Back Directory | [Name]
1,9-Dihydro-2-amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-on e monosodium salt | [CAS]
97845-62-0 | [Synonyms]
Denavir
Unii-p06226385l
PENCICLOVIR SODIUM
sodium
4-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-2-(hy
droxymethyl)butan-1-olate
2-Amino-1,9-dihydro-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-one monosodium salt
1,9-Dihydro-2-amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-6H-purin-6-on e monosodium salt | [Molecular Formula]
C10H14N5O3*Na | [MOL File]
97845-62-0.mol | [Molecular Weight]
277.26 |
| Hazard Information | Back Directory | [Uses]
Antiviral(treatment of herpes virus infections). | [Brand name]
Denavir (Novartis). | [in vivo]
Penciclovir sodium (100 mg/kg; s.c.; daily for 5 days) preventes mortality in mouse[2]. | Animal Model: | Three-week-old female Balb/c mice[2] | | Dosage: | 100 mg/kg | | Administration: | S.c.; daily for 5 days | | Result: | Reduced virus titres in the respiratory organs of both w/t- and PR3-infected mice. |
| [IC 50]
HSV-1: 0.5 μg/mL (EC50); HSV-2: 0.8 μg/mL (EC50) | [storage]
Store at -20°C |
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