| Identification | Back Directory | [Name]
capoamycin | [CAS]
97937-29-6 | [Synonyms]
AC54
AC-54
AC 54
capoamycin
9-[4-O-(1-Oxo-2,4-decadienyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]-4a,12b-dihydro-4a,8,12b-trihydroxy-3-methylbenz[a]anthracene-1,7,12(4H)-trione | [Molecular Formula]
C35H38O10 | [MDL Number]
MFCD01771067 | [MOL File]
97937-29-6.mol | [Molecular Weight]
618.68 |
| Hazard Information | Back Directory | [Description]
Capoamycin is an insotatracine antibiotic. It has been investigated for anti tumor properties. | [Uses]
Capoamycin is an antibiotic. Capoamycin shows antimicrobial and antitumor activity[1]. | [in vivo]
Capoamycin (1.25-10 mg/kg/day, IP ) shows an antitumor activity against Ehrlich mouse ascites carcinoma. Capoamycin causes prolongation of the life spans of treated mice[1].
The LD50 for Capoamycin in mice was approximately 15 mg/kg (ip)[1].
| [References]
[1] Hayakawa Y, et al. Studies on the isotetracenone antibiotics. I. Capoamycin, a new antitumor antibiotic. J Antibiot (Tokyo). 1985 Jul;38(7):957-9. DOI:10.7164/antibiotics.38.957 |
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