ChemicalBook--->CAS DataBase List--->98296-48-1

98296-48-1

98296-48-1 Structure

98296-48-1 Structure
IdentificationBack Directory
[Name]

GANODERIC ACID C2(SH)
[CAS]

98296-48-1
[Synonyms]

GANODERIC ACID C2(SH)
Pirlindole Impurity 1 Hydrobromide
Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,15α)- ’
(3beta,15alpha)-3,7,15-Trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid
Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,15α)- (9CI)
Ganoderic acid C2, 98%, from from Ganoderma Lucidum(Leyss. ex Fr.) Karst.
[Molecular Formula]

C30H46O7
[MOL File]

98296-48-1.mol
[Molecular Weight]

518.68
Chemical PropertiesBack Directory
[density ]

1.22±0.1 g/cm3 (20 ºC 760 Torr)
[solubility ]

Methanol: soluble
[form ]

A solid
Hazard InformationBack Directory
[Chemical Properties]

ex Reishi
[Uses]

(Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 μM[[1][2].
[References]

[1] Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73. DOI:10.1016/j.jpba.2012.11.024
[2] Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3. DOI:10.1055/s-0030-1249782
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