Identification | Back Directory | [Name]
GANODERIC ACID C2(SH) | [CAS]
98296-48-1 | [Synonyms]
GANODERIC ACID C2(SH) Pirlindole Impurity 1 Hydrobromide Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,15α)- ’ (3beta,15alpha)-3,7,15-Trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid Lanost-8-en-26-oic acid, 3,7,15-trihydroxy-11,23-dioxo-, (3β,15α)- (9CI) Ganoderic acid C2, 98%, from from Ganoderma Lucidum(Leyss. ex Fr.) Karst. | [Molecular Formula]
C30H46O7 | [MOL File]
98296-48-1.mol | [Molecular Weight]
518.68 |
Hazard Information | Back Directory | [Chemical Properties]
ex Reishi | [Uses]
(Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 μM[[1][2]. | [References]
[1] Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73. DOI:10.1016/j.jpba.2012.11.024 [2] Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3. DOI:10.1055/s-0030-1249782 |
|
|