| Identification | Back Directory | [Name]
troponin I (104-115) | [CAS]
98353-69-6 | [Synonyms]
troponin I (104-115)
Tni peptide (104-115)
Ac-Gly-lys-phe-lys-arg-pro-pro-leu-arg-arg-val-arg-NH2
L-Argininamide, N-acetylglycyl-L-lysyl-L-phenylalanyl-L-lysyl-L-arginyl-L-prolyl-L-prolyl-L-leucyl-L-arginyl-L-arginyl-L-valyl-
(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-acetamidoacetyl)amino]-6-aminohexanoyl]amino]-3-phenylpropanoyl]amino]-6-aminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide | [Molecular Formula]
C70H123N27O13 | [MOL File]
98353-69-6.mol | [Molecular Weight]
1550.9 |
| Hazard Information | Back Directory | [Description]
Troponin I (104-115) is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of heart attack. It occurs in different plasma concentration but the same circumstances as troponin T - either test can be performed for confirmation of cardiac muscle damage and laboratories usually offer one test or the other._x000D_
Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character. |
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