ChemicalBook--->CAS DataBase List--->98548-90-4

98548-90-4

98548-90-4 Structure

98548-90-4 Structure
IdentificationBack Directory
[Name]

Methyl 3-pyrrolidinecarboxylate
[CAS]

98548-90-4
[Synonyms]

Zinc04202762
Zinc04202763
METHYL-PROLINATE
METHYL 3-PYRROLIDINECARBOXYLATE
METHYL PYRROLIDINE-3-CARBOXYLATE
methyl pyrrolidine-3-carboxylate.HCl
NUR NOCH ALS AST63827 !! METHYL-PROLINATE
3-Pyrrolidinecarboxylic acid methyl ester
PYRROLIDINE-3-CARBOXYLIC ACID METHYL ESTER
(72057-18-2) methyl 3-pyrrolidinecarboxylate
[Molecular Formula]

C6H11NO2
[MDL Number]

MFCD03788461
[MOL File]

98548-90-4.mol
[Molecular Weight]

129.16
Chemical PropertiesBack Directory
[Boiling point ]

92 °C(Press: 17 Torr)
[density ]

1.055±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
[pka]

9.42±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P302+P352-P305+P351+P338
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36/37/39
Questions And AnswerBack Directory
[Application]

Methyl 3-pyrrolidinecarboxylate can be used as a pharmaceutical synthesis intermediate. It can be prepared from benzyl-trimethylsilylmethylamine as a reactant or from methyl 1-benzyl-2-oxopyrrolidine-4-carboxylic acid as a reactant.
Hazard InformationBack Directory
[Synthesis]

Step 1: Benzyl-trimethylsilylmethylamine (100 g, 517 mmol, 1 eq.) was loaded into a 1 L jacketed reactor, followed by 400 mL of THF. The reaction temperature was set to 15 °C and 37% aqueous formaldehyde (53 mL, 647 mmol, 1.25 eq.) was added dropwise o

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