| Identification | Back Directory | [Name]
1,3-Bis-aminooxy propane | [CAS]
98627-69-1 | [Synonyms]
1,3-diaminoxypropane
1,3-Bis-aminooxy propane
Hydroxylamine, O,O'-1,3-propanediylbis- | [Molecular Formula]
C3H10N2O2 | [MDL Number]
MFCD30723214 | [MOL File]
98627-69-1.mol | [Molecular Weight]
106.12 |
| Hazard Information | Back Directory | [Description]
1,3-Bis-aminooxy propane is a samll molecule PEG reagent containing two aminooxy groups. It can react with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | [Uses]
1,3-Bis-aminooxy propane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Alkyl-Chain | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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