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98992-65-5

98992-65-5 Structure

98992-65-5 Structure
IdentificationBack Directory
[Name]

MMP-2/MMP-9 SUBSTRATE II
[CAS]

98992-65-5
[Synonyms]

MMP-2/MMP-9 SUBSTRATE II
MMP COLORIMETRIC SUBSTRATE I
AC-PLG-SCH[CH2CH(CH3)2]-CO-LG-OC2H5
GELATINASE A/GELATINASE B SUBSTRATE II
AC-PRO-LEU-GLY-SCH[CH2CH(CH3)2]-CO-LEU-GLY-OC2H5
AC-PRO-LEU-GLY-(2-MERCAPTO-4-METHYLPENTANOYL)-LEU-GLY-OET
AC-PRO-LEU-GLY-[(S)-2-MERCAPTO-4-METHYL-PENTANOYL]-LEU-GLY-OET
Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester
ethyl 2-[[(2S)-2-[[(2S)-2-[2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]sulfanyl-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetate
[Molecular Formula]

C31H53N5O8S
[MDL Number]

MFCD00236769
[MOL File]

98992-65-5.mol
[Molecular Weight]

655.85
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

water: 1 mg/mL || 50% acetic acid: 10 mg/mL
[form ]

solid
[color ]

white
[Water Solubility ]

water: 1mg/mL
50% acetic acid: 10mg/mL
[Sequence]

Ac-Pro-Leu-Gly-{2-mercapto-4-methylpentanoyl}-Leu-Gly-OEt
Safety DataBack Directory
[WGK Germany ]

WGK 1
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

MMP-2/MMP-9 Substrate, a synthetic colorimetric substrate, is a peptide[1].
[Biological Activity]

Cell permeable: no''Primary Target
Substrate for the rapidsensitiveand continuous spectrophotometric assay of Type IV collagenasesMMP-2 (gelatinase A)and MMP-9 (gelatinase B).''Product does not compete with ATP.''Reversible: no
[References]

[1] Lupia E, et al. Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9. Lab Invest. 2012 Feb;92(2):236-45. DOI:10.1038/labinvest.2011.154
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