| Identification | Back Directory | [Name]
MMP-2/MMP-9 SUBSTRATE II | [CAS]
98992-65-5 | [Synonyms]
MMP-2/MMP-9 SUBSTRATE II
MMP COLORIMETRIC SUBSTRATE I
AC-PLG-SCH[CH2CH(CH3)2]-CO-LG-OC2H5
GELATINASE A/GELATINASE B SUBSTRATE II
AC-PRO-LEU-GLY-SCH[CH2CH(CH3)2]-CO-LEU-GLY-OC2H5
AC-PRO-LEU-GLY-(2-MERCAPTO-4-METHYLPENTANOYL)-LEU-GLY-OET
AC-PRO-LEU-GLY-[(S)-2-MERCAPTO-4-METHYL-PENTANOYL]-LEU-GLY-OET
Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester
ethyl 2-[[(2S)-2-[[(2S)-2-[2-[[(2S)-2-[[(2S)-1-acetylpyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]sulfanyl-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetate | [Molecular Formula]
C31H53N5O8S | [MDL Number]
MFCD00236769 | [MOL File]
98992-65-5.mol | [Molecular Weight]
655.85 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
solid | [color ]
white | [Water Solubility ]
water: 1mg/mL
50% acetic acid: 10mg/mL | [Sequence]
Ac-Pro-Leu-Gly-{2-mercapto-4-methylpentanoyl}-Leu-Gly-OEt |
| Hazard Information | Back Directory | [Uses]
MMP-2/MMP-9 Substrate, a synthetic colorimetric substrate, is a peptide[1]. | [Biological Activity]
Cell permeable: no''Primary Target
Substrate for the rapidsensitiveand continuous spectrophotometric assay of Type IV collagenasesMMP-2 (gelatinase A)and MMP-9 (gelatinase B).''Product does not compete with ATP.''Reversible: no | [References]
[1] Lupia E, et al. Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9. Lab Invest. 2012 Feb;92(2):236-45. DOI:10.1038/labinvest.2011.154 |
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