| Identification | Back Directory | [Name]
Prosaikogenin G | [CAS]
99365-23-8 | [Synonyms]
Prosaikogenin G
[(4R)-16α,23-Dihydroxy-13,28-epoxyoleana-11-ene-3β-yl]6-deoxy-β-D-galactopyranoside
β-D-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy- | [Molecular Formula]
C36H58O8 | [MDL Number]
MFCD34550033 | [MOL File]
99365-23-8.mol | [Molecular Weight]
618.84 |
| Hazard Information | Back Directory | [Uses]
Prosaikogenin G, isolated from the roots of Bupleurum chinensis DC., exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2]. | [References]
[1] Nan Xu, et al. A new saikogenin from the roots of Bupleurum bicaule. Chin J Nat Med. 2014 Apr;12(4):305-8. DOI:10.1016/S1875-5364(14)60060-1
[2] Pei Yu, et al. In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes. Xenobiotica. 2017 Jan;47(1):11-19. DOI:10.3109/00498254.2016.1163753 |
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