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99487-26-0

99487-26-0 Structure

99487-26-0 Structure
IdentificationBack Directory
[Name]

5-(2-fluorophenyl)-8-methyl-3-piperazin-1-yl-9-thia-2,4-diazabicyclo[4.3.0]nona-1,3,5,7-tetraene hydrochloride
[CAS]

99487-26-0
[Synonyms]

MCI-225 hydrochloride
4-(2-Fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno(2,3-D)pyrimidine monohydrochloride
Thieno(2,3-D)pyrimidine, 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)-, monohydrochloride
5-(2-fluorophenyl)-8-methyl-3-piperazin-1-yl-9-thia-2,4-diazabicyclo[4.3.0]nona-1,3,5,7-tetraene hydrochloride
[Molecular Formula]

C17H18ClFN4S
[MOL File]

99487-26-0.mol
Hazard InformationBack Directory
[Uses]

MCI-225 dehydratase is an orally active and selective noradrenaline reuptake inhibitor. MCI-225 dehydratase also is a 5-HT3 antagonist and shows antidepressant effects in vivo[1].
[References]

[1] Eguchi J, et al. The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism[J]. Pharmacology Biochemistry and Behavior, 2001, 68(4): 677-683. DOI:10.1016/s0091-3057(01)00485-3
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