ChemicalBook--->CAS DataBase List--->99844-02-7

99844-02-7

99844-02-7 Structure

99844-02-7 Structure
IdentificationBack Directory
[Name]

4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE
[CAS]

99844-02-7
[Synonyms]

BUTTPARK 16\04-19
4-(4-Methoxyphenyl)pyrimidin-2-
4-(4-Methoxyphenyl)pydimidin-2-amine
4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE
4-(4-METHOXYPHENYL)-2-PYRIMIDINAMINE
2-ANIMO-4-(4-METHOXYPHENYL)PYRIMIDINE
2-AMINO-4-(4-METHOXYPHENYL)PYRIMIDINE
4-(4-METHOXYPHENYL)-2-PYRIMIDINYLAMINE
2-PyriMidinaMine, 4-(4-Methoxyphenyl)-
[4-(4-methoxyphenyl)pyrimidin-2-yl]amine
4-(4-Methoxyphenyl)-2-yl-pyriMidin-2-ylaMine
PyriMidine, 2-aMino-4-(p-Methoxyphenyl)- (6CI)
4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE ISO 9001:2015 REACH
2-Amino-4-(4-methoxyphenyl)pyrimidine, 4-(2-Aminopyrimidin-4-yl)anisole
[Molecular Formula]

C11H11N3O
[MDL Number]

MFCD00665912
[MOL File]

99844-02-7.mol
[Molecular Weight]

201.22
Chemical PropertiesBack Directory
[Melting point ]

189.00°C - 193.00°C
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

22
[HazardClass ]

IRRITANT
[HS Code ]

2933599590
Hazard InformationBack Directory
[Synthesis]

Guanidine nitrate

506-93-4

3-(diMethylaMino)-1-(4-Methoxyphenyl)prop-2-en-1-one

18096-70-3

4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE

99844-02-7

GENERAL METHOD: A mixture of 3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one (1 mmol), guanidine nitrate (2 mmol) and anhydrous K2CO3 (5 mmol) in n-butanol (10 mL) was refluxed for 12 hours. After completion of the reaction, it was cooled to room temperature and the reaction solution was poured into water (30 mL) and extracted with ethyl acetate (3 x 20 mL). The organic layers were combined and concentrated under reduced pressure, and the resulting crude product was purified by recrystallization from ether to give 4-(4-methoxyphenyl)pyrimidin-2-amine.

[References]

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 13, p. 3024 - 3028
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