| Identification | Back Directory | [Name]
Bullatantriol | [CAS]
99933-32-1 | [Synonyms]
Bullatantriol
1β,4β,7α-Trihydroxyeudesmane
1H-Indene-4,7-diol, octahydro-1-(2-hydroxy-2-methylpropyl)-3a,7-dimethyl-, (1R,3aR,4R,7S,7aR)- | [Molecular Formula]
C15H28O3 | [MDL Number]
MFCD14155944 | [MOL File]
99933-32-1.mol | [Molecular Weight]
256.38 |
| Hazard Information | Back Directory | [Uses]
Bullatantriol ((+)?-?Bullatantriol) can be isolated from the roots of Homalomena aromatica. Bullatantriol can promote the proliferation and differentiation of osteoblasts. Bullatantriol also inhibits LPS-induced NO production in BV2 cells[1]. | [Definition]
ChEBI: Bullatantriol is a sesqiterpenoid that is octahydro-1H-indene which is substituted by a 2-hydroxy-2-methylpropyl group at position 1, methyl groups at positions 3a and 7, and hydroxy groups at positions 4 and 7 (the 1R,3aR,4R,7S,7aR stereoisomer). It has been isolated from various Homalomena species. It has a role as a plant metabolite. It is a sesquiterpenoid, a carbobicyclic compound, a secondary alcohol, a tertiary alcohol and a triol. It is functionally related to an oppsit-4(15)-ene-1beta,11-diol. | [References]
[1] Yoon CS, et al. Anti-neuroinflammatory effects of sesquiterpenoids isolated from Nardostachys jatamansi. Bioorg Med Chem Lett. 2018 Jan 15;28(2):140-144. DOI:10.1016/j.bmcl.2017.11.041 |
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