102396-24-7
中文名称
JASPLAKINOLIDE
英文名称
JASPLAKINOLIDE
CAS
102396-24-7
分子式
C36H45BrN4O6
分子量
709.67
MOL 文件
102396-24-7.mol
102396-24-7 结构式
基本信息
中文别名
茉莉花内酯JASPLAKINOLIDE 试剂
英文别名
NSC 613009JASPLAKINOLIDE
GQWYWHOHRVVHAP-DHKPLNAMSA-N
JASPLAKINOLIDE, JASPIS JOHNSTONI
Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem
Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
(3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone
[3S,6R,9R,13S,15R,19S,16E,(+)]-6-[(2-Bromo-1H-indol-3-yl)methyl]-9-(4-hydroxyphenyl)-3,5,13,15,17,19-hexamethyl-2,5,8-triaza-12-oxacyclononadecan-16-ene-1,4,7,11-tetrone
JASPLAKINOLIDE价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-P0027 | Jasplakinolide | 102396-24-7 | 50 μg | 4500元 |
| 2024/08/19 | HY-P0027 | JASPLAKINOLIDE Jasplakinolide | 102396-24-7 | 100μg | 7200元 |
常见问题列表
生物活性
Jasplakinolide 是一种有效的肌动蛋白聚合反应 (actin polymerization) 诱导剂，可以稳定先前存在的肌动蛋白丝。Jasplakinolide 与鬼笔环肽竞争性结合 F-肌动蛋白，Kd 值为 15 nM。Jasplakinolide 是一种来自海洋海绵 (marine sponge) 的天然环状肽，具有抗真菌和抗肿瘤活性。体外研究
Jasplakinolide has an IC
50
of 35 nM for the antiproliferative effect of jasplakinolide on PC3 prostate carcinoma cells.
Jasplakinolide (10 μM; for 2 hours) generates binucleated cells when applied during mitosis. Jasplakinolide induces the formation of F-actin-containing apical extensions in Toxoplasma gondii tachyzoites.
Jasplakinolide (1 mM; for 60 min) induces the formation of actin-containing apical extensions in isolated Toxoplasma gondii tachyzoites fixed.