104746-04-5
中文名称
(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺
英文名称
S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
CAS
104746-04-5
分子式
C15H14N2O2
分子量
254.288
MOL 文件
104746-04-5.mol
更新日期
2025/02/08 09:36:51
104746-04-5 结构式
基本信息
中文别名
(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 英文别名
(10S)-(S)-Licarbazepine
S-10-MONOHYDROXY-DIHYDRO-CARBAMAZEPIN
(S)-10-Monohydroxydihydrocarbamazepine
(10S)-10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE
(S)-10-Monohydroxy-dihydro-carbamazepine (Eslicarbazepine)
(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepin-5-carboxamide
(S)-10-Monohydroxy-10,11-dihydro CarbaMazepine (Eslicarbazepine)
(S)-10-Hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxaMide
5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-
所属类别
有机原料：酰胺类化合物物理化学性质
熔点188-190°C
沸点431.3±55.0 °C(Predicted)
密度1.336
储存条件-20°C冷冻
溶解度可溶于氯仿（轻微、加热）、甲醇（轻微）、吡啶（轻微）
酸度系数(pKa)13.75±0.20(Predicted)
形态固体
颜色白色至淡黄色
InChIInChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1
InChIKeyBMPDWHIDQYTSHX-AWEZNQCLSA-N
SMILESN1(C(N)=O)C2=CC=CC=C2[C@@H](O)CC2=CC=CC=C12
常见问题列表
生物活性
Eslicarbazepine (BIA 2-194) 是一种口服抗惊厥试剂，可用于局部癫痫的辅助研究。体内研究
Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.