106533-51-1
中文名称
化合物 T24534
英文名称
Lanosta-7,9(11),24-trien-21-oic acid, 23-hydroxy-3-oxo-, γ-lactone, (13α,14β,17α,20S,23R)-
CAS
106533-51-1
分子式
C30H42O3
分子量
450.66
MOL 文件
106533-51-1.mol
106533-51-1 结构式
基本信息
中文别名
化合物 T24534 英文别名
Nimolinone11-Nimolinone
D9,11-Nimolinone
Lanosta-7,9(11),24-trien-21-oic acid, 23-hydroxy-3-oxo-, γ-lactone, (13α,14β,17α,20S,23R)-
所属类别
生物化工：抑制剂应用领域
用途一
Nimolinone is presented in EENL. Analysis of the compounds in the EENL by mass spectrometry suggests the presence of nimbolide, 2',3'-dehydrosalannol, 6-desacetyl nimbinene, and nimolinone. Antiproliferative activity of nimbolide and 2',3'-dehydrosalannol in HUVECs. EENL by regulating the genes involved in cellular development and cell death functions could control cell proliferation, attenuate the stimulatory effects of VEGF, and exert antiangiogenic effects. EENL treatment could have a potential therapeutic role during cancer progression.