1142363-52-7
中文名称
EDICOTINIB
英文名称
4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)- 1H-imidazole-2-carboxamide
CAS
1142363-52-7
分子式
C27H35N5O2
分子量
461.6
MOL 文件
1142363-52-7.mol
更新日期
2025/05/12 10:48:36
1142363-52-7 结构式
基本信息
中文别名
化合物EDICOTINIBJNJ-40346527游离态
英文别名
CS-2865JNJ-527
EDICOTINIB
JNJ-40346527
JUJ-40346527
Edicotinib(JNJ-40346527)
JNJ40346527
JNJ 40346527
JNJ-40346527
EDICOTINIB
4-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)- 1H-imidazole-2-carboxamide
1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(4,4-dimethyl-1-cyclohexen-1-yl)-6-(tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)-3-pyridinyl]-
物理化学性质
密度1.19±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO:23.34(Max Conc. mg/mL);50.56(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.54(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.99(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);43.33(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.54(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.99(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);43.33(Max Conc. mM)
酸度系数(pKa)13.82±0.70(Predicted)
形态结晶固体
颜色White to off-white
