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1207440-88-7

中文名称 化合物 T26569
英文名称 Acetamide, N-[5-[4-[(4-chloro-3-fluorophenyl)methyl]-4,5-dihydro-6-methoxy-3,5-dioxo-1,2,4-triazin-2(3H)-yl]-2-fluorophenyl]-
CAS 1207440-88-7
分子式 C19H15ClF2N4O4
分子量 436.8
MOL 文件 1207440-88-7.mol
1207440-88-7 结构式 1207440-88-7 结构式

基本信息

中文别名
化合物 T26569
英文别名
Acetamide, N-[5-[4-[(4-chloro-3-fluorophenyl)methyl]-4,5-dihydro-6-methoxy-3,5-dioxo-1,2,4-triazin-2(3H)-yl]-2-fluorophenyl]-

物理化学性质

密度1.47±0.1 g/cm3(Predicted)
酸度系数(pKa)13.65±0.70(Predicted)

应用领域

用途一
ADX71441 is a GABAB positive allosteric modulator (PAM). ADX71441 increases urinary latencies and reduces the number of urinary events and the total and average urinary volumes. ADX71441 completely inhibits the micturition reflex and induced overflow incontinence in five out of 10 animals. GABAB PAM has potential as a novel approach for the treatment of overactive bladder. It may also mitigate alcoholism and have analgesic effects in the bladder.
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