125314-13-8
中文名称
GSK-3Β抑制剂(CP21R7)
英文名称
CP21R7(CP21)
CAS
125314-13-8
分子式
C19H15N3O2
分子量
317.34
MOL 文件
125314-13-8.mol
更新日期
2025/08/19 10:33:45
125314-13-8 结构式
基本信息
中文别名
化合物CP21R7GSK-3Β抑制剂(CP21R7)
3-(3-氨基苯基)-4-(1-甲基-1H-吲哚-3-基)吡咯-2,5-二酮
英文别名
CP21R7CS-2352
CP21R7(CP21)
CP21 (CP21R7)
3-(3-aminophenyl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione
3-(3-Aminophenyl)-4-(1-methyl-1H-indol-3-yl)pyrrole-2,5-dione
3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-
所属类别
生物化工：激动剂抑制剂物理化学性质
沸点627.4±55.0 °C(Predicted)
密度1.37±0.1 g/cm3(Predicted)
储存条件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度insoluble in EtOH; insoluble in H2O; ≥14.25 mg/mL in DMSO
酸度系数(pKa)7.79±0.60(Predicted)
形态结晶固体
颜色Yellow to orange
GSK-3Β抑制剂(CP21R7)价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-100207 | GSK-3Β抑制剂(CP21R7) CP21R7 | 125314-13-8 | 10mM * 1mLin DMSO | 768元 |
| 2025/05/22 | HY-100207 | GSK-3Β抑制剂(CP21R7) CP21R7 | 125314-13-8 | 5mg | 1100元 |
| 2025/05/22 | S7954 | GSK-3Β抑制剂(CP21R7) CP21R7 (CP21) | 125314-13-8 | 5mg | 1204.9元 |
常见问题列表
生物活性
CP21R7 (CP21) 是一种有效的、选择性的GSK-3β抑制剂，能有效激活经典Wnt信号通路。靶点
| Target | Value |
|
GSK-3β
(Cell-free assay) |
体外研究
CP21R7 (Compound 9) is a selective inhibitor of GSK-3β, with an IC 50 of 1.8 nM; the IC 50 of CP21R7 against PKCα is 1900 nM. CP21R7 (CP21, 3 μM) potently activates canonical Wnt signaling with highest activity. CP21 significantly increases total levels of intracellular β-catenin. CP21 combined with BMP4 induces commitment of hPSCs towards mesoderm.