1306684-90-1
1306684-90-1 结构式
物理化学性质
沸点533.2±53.0 °C(Predicted)
密度1.027±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMF: 20 mg/ml; Ethanol: 10 mg/ml
酸度系数(pKa)2.25±0.10(Predicted)
形态结晶固体
InChIKeyXWVBRTAQHMKHCE-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1
应用领域
用途一
BMP-22 is an inhibitor of autotaxin. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) and inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis.