1332290-68-2
英文名称
Benzene, 4-[(1E)-2-[2-(3,4-dimethoxyphenyl)-3-cyclohexen-1-yl]ethenyl]-1,2-dimethoxy-
CAS
1332290-68-2
分子式
C24H28O4
分子量
380.48
MOL 文件
1332290-68-2.mol
1332290-68-2 结构式
应用领域
用途一
NMac1is a small molecule phenylbutenoid dimer that has novel anti-proliferative effect only under glucose starvation in metastatic breast cancer cells. NMac1 causes significant activation of AMPK by decreasing ATP synthesis, lowers mitochondrial membrane potential (MMP, ΔΨm), and inhibits oxygen consumption rate (OCR) under glucose starvation. These effects of NMac1 are provoked by a consequence of OXPHOS complex I inhibition.