1426164-52-4
中文名称
马来酰亚胺-酰胺-PEG2-酸
英文名称
Bis-Mal-Lysine-PEG4-acid
CAS
1426164-52-4
分子式
C31H45N5O13
分子量
695.71
MOL 文件
1426164-52-4.mol
1426164-52-4 结构式
基本信息
中文别名
马来酰亚胺-酰胺-PEG2-酸双马来酰亚胺-赖氨酸-四聚乙二醇-羧酸
英文别名
Bis-Mal-Lysine-PEG4-acid4,7,10,13-Tetraoxa-16,23-diazahexacosanoic acid, 26-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-18-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-17,24-dioxo-, (18S)-
应用领域
用途一
Bis-Mal-Lysine-PEG4-acid is a PEG linker with two maleimide groups which can react with thiols from pH ranges of 6.5 to 7.5 to from a thiolester bond. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media.