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1443331-94-9

中文名称 [2H6]-恩杂鲁胺
英文名称 [2H6]-Enzalutamide
CAS 1443331-94-9
分子式 C21H16F4N4O2S
分子量 464.44
MOL 文件 1443331-94-9.mol
更新日期 2024/09/27 12:11:49
1443331-94-9 结构式 1443331-94-9 结构式

基本信息

中文别名
恩杂鲁胺-[D6]
[2H6]-恩杂鲁胺
英文别名
[2H6]-Enzalutamide
Enzalutamide D6Q: What is Enzalutamide D6 Q: What is the CAS Number of Enzalutamide D6 Q: What is the storage condition of Enzalutamide D6 Q: What are the applications of Enzalutamide D6

应用领域

用途一
Isotope labelled MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.

常见问题列表

概述
[2H6]-恩杂鲁胺 是一种氘标记的 Enzalutamide (MDV3100)。Enzalutamide 是一种雄激素受体 (AR) 拮抗剂,在 LNCaP 前列腺细胞中 IC50 为 36 nM。
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