1563176-59-9
中文名称
5,6-反式-曲伏前列素
英文名称
5,6-trans Travoprost
CAS
1563176-59-9
分子式
C26H35F3O6
分子量
500.55
MOL 文件
1563176-59-9.mol
更新日期
2025/06/06 08:33:44

基本信息
中文别名
曲伏前列素杂质 295,6-反式-曲伏前列素
5,6-反式-曲伏前列素杂质
5,6-TRANS-曲伏前列素
5,6-TRANS 曲沃前列素
英文别名
5,6-trans TravoprostTravoprost Impurity 29
MKPLKVHSHYCHOC-JPVYXPJZSA-N
Travoprost Impurity 2(5,6-trans-Travoprost)
isopropyl (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate
(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester
(5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoroMethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5E)-
5,6-trans-Travoprost/(5E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester
5,6-trans-TravoprostQ: What is 5,6-trans-Travoprost Q: What is the CAS Number of 5,6-trans-Travoprost Q: What is the storage condition of 5,6-trans-Travoprost Q: What are the applications of 5,6-trans-Travoprost
所属类别
医药中间体:原料药中间体物理化学性质
沸点584.8±50.0 °C(Predicted)
密度1.245±0.06 g/cm3(Predicted)
储存条件Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度氯仿(微溶)、二氯甲烷(微溶)、甲醇(微溶)
酸度系数(pKa)13.43±0.20(Predicted)
形态Oil
颜色透明无色至淡黄色厚
InChIKeyMKPLKVHSHYCHOC-JPVYXPJZSA-N
SMILESC(OC(C)C)(=O)CCC/C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COC1=CC=CC(C(F)(F)F)=C1
常见问题列表
概述
5,6-反式-曲伏前列素 是 Travoprost (HY-B0584) 的异构体,可作为实验中的对照化合物。Travoprost (Fluprostenol isopropyl ester) 是一种异丙基酯前体,是一种高亲和力的,选择性的 FP 前列腺素全受体激动剂。Travoprost 有降眼压功效,有潜力应用于青光眼和眼高压。