160743-62-4
基本信息
DMG-PEG2000阳离子脂质体
ONPATTRO磷脂DMG-PEG2000
1,2-二肉豆蔻酰基-SN-甘油-3-甲氧基聚乙二醇
1,2-二肉豆蔻酰-RAC-甘油-3-甲氧基聚乙二醇2000
Methoxypoly(ethylene glycol) dimyristoyl glycerol
Polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG]
1,?2-?Dimyristoyl-?sn-?glycero-?3-?methoxypolyethylene glycol
1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-112764 | DMG-PEG2000 DMG-PEG 2000 | 160743-62-4 | 10 mg | 323元 |
| 2025/05/22 | HY-112764 | DMG-PEG 2000 | 160743-62-4 | 25 mg | 500元 |
| 2025/05/22 | HY-112764 | DMG-PEG 2000 | 160743-62-4 | 50 mg | 750元 |
常见问题列表
NP-3 (0.05-1.6 mg/mL; 24 hours) does not decrease the cytotoxicity of cells in 293T, HepG2, A549, and HeLa cell lines, but the DPPC and DMG-PEG coated nanoparticles reduce cell cytotoxicity. In addition, the transfection efficiency of DPPC/DMG-PEG/(lPEI/DNA) nanoparticles (NP-3) in 293 cells is improved, and the maximum transfection efficiency (∼76% eGFP positive cells) is observed.
NP-3 (oral administration; 150 μg DNA per mouse; single dose) at 12, 24, and 36 h postadministration, luciferin substrate is intraperitoneally injected to verify its permeability. NP-3 group maintains high luciferase expression in the liver, lung, and intestine areas 12-24 h post-treatment.Additionally, NP-3 exhibits 1.5 times higher signal intensity than that of NP-1 or NP-2 group from 12 to 24 h postoral administration.