182369-73-9
中文名称
消旋5 -伏立康唑
英文名称
rac 5-Desfluoro Voriconazole
CAS
182369-73-9
分子式
C16H15F2N5O
分子量
331.32
MOL 文件
182369-73-9.mol
更新日期
2026/08/04 11:21:56
182369-73-9 结构式
基本信息
中文别名
伏立康唑杂质B消旋5 -伏立康唑
伏立康唑EP杂质B
伏立康唑 EP B
外消旋5-去氟伏立康唑
伏立康唑杂质B (EP)
(+/-)-单去氟伏立康唑
伏立康唑相关化合物D(USP)
VORICONAZOLE EP杂质 B
英文别名
Voriconazole IMpurity Brac 5-Desfluoro Voriconazole
(+/-)-DesMonofluono Voriconazole
Voriconazole Impurity 18(Voriconazole EP Impurity B)
(2R,3S)-2-(2,4-difluorophenyl)-3-pyrimidin-4-yl-1-(1,2,4-triazol-1-yl)butan-2-ol
(2S,3S)-2-(2,4-difluorophenyl)-3-(pyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
(2RS,3SR)-2-(2,4-Difluorophenyl)-3-pyrimidin-4-yl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Voriconazole EP Impurity B/ Voriconazole Related Compound D (Desfluoro rac-Voriconazol)
(R*,S*)-α-(2,4-Difluorophenyl)-β-Methyl-α-(1H-1,2,4-triazol-1-ylMethyl)-4-pyriMidineethanol
4-Pyrimidineethanol, α-(2,4-difluorophenyl)-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (R*,S*)- (9CI)
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
沸点513.3±60.0 °C(Predicted)
密度1.37±0.1 g/cm3(Predicted)
储存条件2-8°C
溶解度Chloroform (Slightly), Methanol (Slightly)
酸度系数(pKa)11.76±0.29(Predicted)
形态neat
主要应用pharmaceutical (small molecule)
InChI1S/C16H15F2N5O/c1-11(15-4-5-19-8-21-15)16(24,7-23-10-20-9-22-23)13-3-2-12(17)6-14(13)18/h2-6,8-11,24H,7H2,1H3/t11-,16+/m0/s1
InChIKeyZVQLILUCRUIFNH-MEDUHNTESA-N
SMILESFc1c(ccc(c1)F)[C@](O)([C@@H](C)c3ncncc3)C[n]2ncnc2
