1910803-72-3
中文名称
BITOIN-PEG2-AZIDE
英文名称
Biotin-PEG2-azide
CAS
1910803-72-3
分子式
C16H28N6O4S
分子量
400.5
MOL 文件
1910803-72-3.mol
更新日期
2025/05/10 20:29:18
1910803-72-3 结构式
基本信息
中文别名
生物素-PEG2-叠氮BIOTIN-二聚乙二醇-叠氮
英文别名
BITOIN-PEG2-AZIDEBiotin-PEG2-azide
1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hexahydro-2-oxo-
应用领域
用途一
Biotin-PEG2-azide is PEG derivative containing a biotin group and an azide group. The azide group can react with either alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.