2364-67-2
中文名称
棕榈酰肉碱
英文名称
PALMITOYL CARNITINE
CAS
2364-67-2
分子式
C23H45NO4
MOL 文件
2364-67-2.mol
更新日期
2025/04/25 10:56:49
2364-67-2 结构式
基本信息
中文别名
棕榈酰-L-左旋肉碱 英文别名
C02990Palmitylcarnitine
L-Palmitoylcarnitine
Palmityl-L-carnitine
Palmitoyl L-carnitine
Hexadecanoylcarnitine
O-palmitoyl-L-carnitine
Palmitoyl-L-Carnitine solution
Palmitoyl-L-carnitine >=97.0% (TLC)
(3R)-3-hexadecanoyloxy-4-trimethylazaniumylbutanoate
物理化学性质
储存条件2-8°C
溶解度Soluble in DMSO
形态liquid
旋光性 (optical activity)[α]/D -17±2°, c = 1 in methanol
BRN4152034
棕榈酰肉碱价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-113147 | 棕榈酰肉碱 L-Palmitoylcarnitine | 2364-67-2 | 1 mg | 1300元 |
| 2025/02/08 | HY-113147 | 棕榈酰肉碱 L-Palmitoylcarnitine | 2364-67-2 | 5 mg | 3900元 |
常见问题列表
生物活性
L-Palmitoylcarnitine 是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine 通过与 Kir6.2 的相互作用抑制 KATP 通道活性，而不影响单通道电导。靶点
|
Kir6.2
|
Human Endogenous Metabolite
|
体外研究
L-Palmitoylcarnitine (1 µM) inhibits K
ATP
channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC
50
fell from 62 to 30 µM).
Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the K
ATP
channel function mainly through the interaction with endogenous PI cascade, especially PIP2.