37413-91-5
中文名称
21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯
英文名称
3,20-Dioxopregna-1,4,9(11),16-tetraen-21-yl acetate
CAS
37413-91-5
分子式
C23H26O4
分子量
366.45
MOL 文件
37413-91-5.mol
更新日期
2025/05/15 20:36:31
37413-91-5 结构式
基本信息
中文别名
醋酸四烯物泼尼松杂质12
醋酸四烯物(3TR)
布地奈德杂质对照品6
16-四烯-3,20-二酮-21-醋酸酯
21-乙酰氧基孕甾-1,4,9(11),16-四烯-3,20-酮
21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯
21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯 100G
2-((8S,10S,13S,14S)-10,13-二甲基-3-氧代-6,7,8,10,12,13,14,15-八氢-3H-环戊二烯并[A]菲-17-基)-2-氧代乙基 乙酸酯
英文别名
37413-91-516-tetraen-21-yl
Tetraene acetate[3TR]
Prednisone Impurity 12
Acetate tetraene Matter
Tetraen-acetic acid complex
Pregna-1,4,9(11),16-tetraen
21-Hydroxy-1,4,9(11)-tetraene 21-acetate
21-Acetoxypregna-1,4,9(11),16-tetrene-3,20-dione
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
常见问题列表
用途
醋酸四烯物(21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯,3TR)是合成曲安奈德、地塞米松、布地奈德等甾体药物的重要中间体生物活性
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione 是 delta 9,11 类固醇类合成的中间体 (intermediate)，如 Vamorolone (HY-109017)。delta 9,11 steroids 是糖皮质激素的修饰后的产物，具有抗炎 (anti-inflammatory) 特性。delta 9,11 类固醇类可以用作保护细胞损伤(脂质过氧化)和抑制新生血管的试剂。体外研究
Δ9,11 derivatives are designed and developed to stably incorporate into cell membranes and inhibit lipid peroxidation without glucocorticoid or mineralocorticoid activities, thus avoiding side effects associated with traditional corticosteroids. VBP15 acts as a lead compound due to potent NF-κB inhibition and GR translocation similar to prednisone and dexamethasone, lack of transactivation properties, and good bioavailability.
21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-136340 | 21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione | 37413-91-5 | 5 mg | 312元 |
| 2025/02/08 | HY-136340 | 21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione | 37413-91-5 | 10mg | 500元 |
| 2025/02/08 | HY-136340 | 21-羟基孕甾-1,4,9(11),16-四烯-3,20-二酮-21-醋酸酯 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione | 37413-91-5 | 10mM * 1mLin DMSO | 550元 |