51053-40-8
51053-40-8 结构式
基本信息
中文别名
脂霉素Α脂霉素Α
Α-脂霉素
ALPHA-脂霉素
英文别名
α-LipomycinLipomycin α
α-Lipomycin
alpha-Lipomycin
LipoMycin, alpha-
4-[13-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-10,12,14-trimethyl-1-oxopentadeca-2,4,6,8,10-pentenyl]-2,5-dihydro-3-hydroxy-1-methyl-5-oxo-1H-pyrrole-2-propanoic acid
1H-Pyrrole-2-propanoic acid, 4-[13-[(2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-10,12,14-trimethyl-1-oxo-2,4,6,8,10-pentadecapentaen-1-yl]-2,5-dihydro-3-hydroxy-1-methyl-5-oxo-
物理化学性质
沸点804.975±65.00 °C(Press: 760.00 Torr)(predicted)
密度1.235±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
储存条件-20°C储存
溶解度DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
酸度系数(pKa)4.500±1.00(predicted)
形态固体
应用领域
用途一
α-Lipomycin is an unusual pentaenone tetramic acid first isolated from Streptomyces aureofaciens in 1972. Lipomycin has potent Gram positive antibacterial activity with no activity against fungi, including yeasts. The antibiotic activity is antagonized by lecithin and some sterols, implying alterations of the cell membrane.