520-11-6
520-11-6 结构式
基本信息
泽兰叶黄素
6-甲氧基藤黄菌素
泽兰黄酮(6-甲氧基藤黄菌素
6-甲氧基木犀草素, 来源于泽兰
Eurafolin
EUPAFOLIN
NSC 122416
6-METHOXYLUTEOLIN
Eupafolin(Nepetin)
Eupafloin 6-Methoxyluteolin
Eupafolin(Nepetin,NSC 122416)
-5,7-dihydroxy-6-methoxy-4H-chromen-4-one
6-Methoxyluteolin, 98%, from Lycopus lucidus Turcz. ex Benth.
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-N2572 | 泽兰黄酮 Nepetin | 520-11-6 | 1 mg | 800元 |
| 2025/02/08 | HY-N2572 | 6-甲氧基藤黄菌素 Nepetin | 520-11-6 | 5mg | 2000元 |
| 2025/02/08 | HY-N2572 | 6-甲氧基藤黄菌素 Nepetin | 520-11-6 | 10mg | 3200元 |
常见问题列表
泽兰黄酮(6-Methoxyluteolin) 是从 Eupatorium ballotaefolium HBK 分离的天然类黄酮，具有有效的抗炎活性。Nepetin 在 ARPE-19 细胞中抑制 IL-6，IL-8 和 MCP-1 分泌，IC50 值分别为 4.43 μM、3.42 μM 和 4.17 μM。
Pretreatment with Nepetin dose-dependently inhibited IL-6, IL-8 and MCP-1 secretion with
IC
50
values of 4.43, 3.42 and 4.17 μM, respectively.
Nepetin (2.5-10 μM; 25 hours; ARPE-19 cells) treatment suppresses IL-1β-induced cytokine (IL-6, IL-8 and MCP-1) expression at mRNA level in ARPE-19 cells.
Nepetin (2.5-10 μM; 1.5 hours; ARPE-19 cells) treatment dose-dependently inhibits phosphorylation of IKKα/β and IκBα, and nuclear translocation of p65. Nepetin decreases the level of phosphorylated ERK1/2, JNK and p38 MAPK in activated ARPE-19 cells.
RT-PCR
| Cell Line: | ARPE-19 cells |
| Concentration: | 2.5 μM, 5 μM, 10 μM |
| Incubation Time: | 25 hours |
| Result: | Suppressed the mRNA expression of IL-6, IL-8 and MCP-1 in ARPE-19 cells. |
Western Blot Analysis
| Cell Line: | ARPE-19 cells |
| Concentration: | 2.5 μM, 5 μM, 10 μM |
| Incubation Time: | 1.5 hours |
| Result: | Dose-dependently inhibited phosphorylation of IKKα/β and IκBα, and nuclear translocation of p65. Decreased the level of phosphorylated ERK1/2, JNK and p38 MAPK in activated ARPE-19 cells. |