537-46-2

熔点143°C (estimate)

沸点230.33°C (estimate)

密度0.9285 (estimate)

折射率1.5105 (estimate)

闪点9℃

储存条件2-8°C

酸度系数(pKa)10.38±0.10(Predicted)

警示词危险

危险品运输编号1851

WGK Germany1

REACH 注册登记Active

危险等级6.1(b)

包装类别III

毒性A widely abused drug; a sympathomimetic and central stimulant that has been used clinically as an anorectic agent. The use of methamphetamine and related drugs in treating obesity is, however, now generally discredited. It may cause elevation of blood pressure, palpitation, and tachycardia, as well as various CNS effects, including psychotic effects at higher doses. Chronic use of methamphetamine and related compounds, especially at high doses as often occurs with drug abuse, can cause a condition often indistinguishable from schizophrenia. Abrupt withdrawal may cause fatigue, depression, and sleep changes. Methamphetamine is an indirect-acting adrenergic and dopamine agonist that acts principally to release endogenous catecholamines, thereby increasing their synaptic availability. Many of its actions can be blocked by adrenergic and dopamine antagonists. The i.p. LD50 in mice is 70 mg/kg.