56092-82-1
56092-82-1 结构式
基本信息
链霉菌属载体
离子霉素钙盐
罗红霉素钙盐
碘霉素(钙盐)
罗红霉素(游离酸)
罗红霉素钙盐,1MG
罗红霉素钙盐(链霉菌属载体)
IONOMYCIN CAICIUM SALT 钙盐
IONOMYCIN CALCIUM SALT 钙离子霉素
Ionomycin,Ion
IONOMYCIN (CA)
SQ23377 calcium
IONOMYCIN CA-SALT
ionomycin calcium
Calcium ionomycin.
Ionomycin Ca2+ salt
IONOMYCIN CALCIUM SALT
IONOMYCIN CALCIUM SALT 1MG
物理化学性质
常见问题列表
Calcium ionophore
Ionomycin is a Calcium ionophore and an antibiotic produced by
Streptomyces conglobatus
.
Addition of 2 μM Ionomycin to LCLC 103H cells causes an instantaneous increase in intracellular Ca
2+
concentration from 50 to 180 nM. DNA and protein analysis in Ionomycin-treated cultures revealed DNA fragmentation and PARP cleavage to an 85-kDa fragment typical of caspase-mediated apoptosis. Necrosis could be detected in ~1-5% of the Ionomycin treated cells. Caspase activation in whole cells was followed by monitoring the increase in activity against Ac-DEVD-amc following Ionomycin treatment.
Ionomycin-mediated cleavage and exosome release. Following Ionomycin exposure, medium conditioned by SKOV3ip cells had increased amounts of exosomes containing the L1-32 cleavage fragment.