581098-48-8
中文名称
p38 MAP Kinase Inhibitor III
英文名称
p38 MAP Kinase Inhibitor III
CAS
581098-48-8
分子式
C23H21FN4S
分子量
404.5
MOL 文件
581098-48-8.mol
581098-48-8 结构式
基本信息
英文别名
(S)-p38 MAPK Inhibitor III(S)-p38 MAP Kinase Inhibitor III
p38 MAP Kinase Inhibitor III - CAS 581098-48-8 - Calbiochem
(S)-p-38 MAPK Inhibitor III,(S) p38 MAPK Inhibitor III,(S)p38 MAPK Inhibitor III
4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-2-pyridinamine
2-Pyridinamine, 4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-
物理化学性质
熔点117-119 °C
沸点589.4±60.0 °C(Predicted)
密度1.30±0.1 g/cm3(Predicted)
储存条件+2C to +8C
溶解度DMF: 20 mg/mL; DMSO: 12 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/mL
酸度系数(pKa)9.07±0.10(Predicted)
形态Yellow solid
颜色White to off-white
InChI1S/C23H21FN4S/c1-15(16-6-4-3-5-7-16)26-20-14-18(12-13-25-20)22-21(27-23(28-22)29-2)17-8-10-19(24)11-9-17/h3-15H,1-2H3,(H,25,26)(H,27,28)
InChIKeyVXPWQNBKEIVYIS-UHFFFAOYSA-N
SMILESFc1ccc(cc1)c2[nH]c(nc2c3cc(ncc3)NC(C)c4ccccc4)SC