68077-27-0
中文名称
盐酸诺氟沙星
英文名称
Norfloxacinehydrochloride
CAS
68077-27-0
分子式
C16H19ClFN3O3
分子量
355.792
MOL 文件
68077-27-0.mol
更新日期
2023/11/10 17:38:38
68077-27-0 结构式
基本信息
中文别名
NORFL氧杂CIN盐酸盐 英文别名
NorfloxacineHClNorfloxacinehydrochloride
Hydrochloric acid and norfloxacin
Norfloxacinehydrochloride USP/EP/BP
所属类别
原料药：喹诺酮类药常见问题列表
生物活性
Norfloxacin hydrochloride (MK-0366 hydrochloride) 是广谱抗生素，能通过结合DNA旋转酶抑制革兰氏阳性和阴性菌。靶点
DNA gyrase; Antibacterial.
体外研究
Norfloxacin hydrochloride (MK-0366 hydrochloride) is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division.There are currently three approved uses in the adult population (one of which is restricted) and the other ineffective due to bacterial resistance.