74389-68-7
74389-68-7 结构式
基本信息
C16PAF
ACGEPC
PAF (C16)
C16-02:0 PC
PAF (C16),99%
C16-PAF-acether
C16 ENANTIOMERIC PAF
PLATELET ACTIVATING FACTOR
PLATELET ACTIVATING FACTOR-16
物理化学性质
安全数据
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-108635 | Β-乙酰基-Γ-O-十六烷基-L-Α-卵磷脂 C16-PAF | 74389-68-7 | 1 mg | 677元 |
| 2025/02/08 | HY-108635 | Β-乙酰基-Γ-O-十六烷基-L-Α-卵磷脂 C16-PAF | 74389-68-7 | 5mg | 1600元 |
| 2025/02/08 | HY-108635 | Β-乙酰基-Γ-O-十六烷基-L-Α-卵磷脂 C16-PAF | 74389-68-7 | 10mM * 1mLin DMSO | 1840元 |
常见问题列表
|
Human Endogenous Metabolite
|
ERK
|
MEK
|
C16-PAF (PAF (C16); 0.5-1.5 μM; for 24 hours) elicits significant concentration-dependent neuronal loss in PAFR
−/−
but not PAFR
+/+
cultures. C16-PAF (1 μM) elicits neuronal death in PAFR
−/−
cells infected with EGFP alone.
C16-PAF (1 μM; for 24 hours) activates caspase 7 but not caspase 3 in PAFR
−/−
neurons.
C16-PAF is synthesized by two distinct pathways; the remodeling pathway and the de novo synthesis pathway. C16-PAF acts by binding to a unique G-protein-coupled seven transmembrane receptor.
C16-PAF (1-25 μg/ml; 6, 12, 24 h) inhibits
M. smegmatis
and
M. bovis
BCG growth in a time-dependent manner.
Cell Viability Assay
| Cell Line: | Cerebellar granule neurons (CGNs) from PAFR −/− and PAFR +/+ mice |
| Concentration: | 0.5-1.5 μM |
| Incubation Time: | 24 hours |
| Result: | Elicited significant concentration-dependent neuronal loss in PAFR −/− but not PAFR +/+ cultures in serum-free media. |
Western Blot Analysis
| Cell Line: | CGNs |
| Concentration: | 1 μM |
| Incubation Time: | 24 hours |
| Result: | Activated caspase 7 but not caspase 3 in PAFR −/− neurons. |