87116-72-1
87116-72-1 结构式
基本信息
中文别名
替莫贝松 英文别名
TimobesoneTimobesone [inn]
9-Fluoro-11β,17α-dihydroxy-16β-methyl-3-oxoandrosta-1,4-diene-17-carbothioic acid S-methyl ester
Androsta-1,4-diene-17-carbothioic acid, 9-fluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-methyl ester, (11β,16β,17α)-
物理化学性质
沸点553.0±50.0 °C(Predicted)
密度1.30±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)12.13±0.70(Predicted)
常见问题列表
生物活性
Timobesone是一种局部皮质类固醇，但从未上市。体外研究
The increase in the solubility of Timobesone acetate in the micellar solutions is dependent on the type and concentration of surfactant. The solubilizing capacity of the surfactant micelles and the distribution coefficient of Timobesone acetate in aqueous micellar solutions are found to increase with increasing length of the hydrophobic fatty acid group.