87625-92-1
中文名称
硝苯地平杂质9
英文名称
Nifedipine Impurity 9
CAS
87625-92-1
分子式
C15H15NO5
分子量
289.28
MOL 文件
87625-92-1.mol
更新日期
2025/07/01 11:39:08
87625-92-1 结构式
基本信息
中文别名
尼卡地平杂质A硝苯地平杂质9
尼卡地平杂质85
尼卡地平杂质07
英文别名
Nifedipine Impurity 9Nicardipine Impurity A
Nicardipine Impurity85
Nicardipine Cyclohexenone Impurity
Methyl 2-methyl-6-(3-nitrophenyl)4-oxocyclohex-2-ene-1-carboxylate
methyl 3-methyl-3'-nitro-5-oxo-1,2,5,6-tetrahydro-[1,1'-biphenyl]-2-carboxylate
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
沸点419.3±45.0 °C(Predicted)
密度1.269±0.06 g/cm3(Predicted)
溶解度Chloroform (Slightly), Methanol (Slightly, Sonicated)
形态Thick Oil to Solid
颜色Off-White to Yellow
InChIInChI=1S/C15H15NO5/c1-9-6-12(17)8-13(14(9)15(18)21-2)10-4-3-5-11(7-10)16(19)20/h3-7,13-14H,8H2,1-2H3
InChIKeyDRIQTXKHWGPNKI-UHFFFAOYSA-N
SMILESC1(C(OC)=O)C(C2=CC=CC([N+]([O-])=O)=C2)CC(=O)C=C1C
应用领域
用途一
Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate is a nicardipine impurity. Also, it is derived from Methyl Acetoacetate (O848425), which is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.