GSK163090
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- CAS号:
- 844903-58-8
- 英文名:
- GSK163090
- 英文别名:
- CS-2298;GSK163090;GSK163090 (GSK-163090;GSK163090, 10 mM in DMSO;GSK163090; GSK-163090; GSK 163090.;5-HT1A/B/D receptor antagonist GS163090;1-(3-{2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl}phenyl)imidazolidin-2-one;1-[3-[2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl]phenyl]-2-imidazolidinone;2-Imidazolidinone,1-[3-[2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl]phenyl]-;Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,anxiolytic,SerT,inhibit,5-HT1B,5-HT1D,5-HT Receptor,GSK-163090,GSK 163090,Serotonin Receptor,P-glycoprotein
- 中文名:
- GSK163090
- 中文别名:
- 化合物GSK163090;化合物GSK163090,10 MM DMSO 溶液;1-[3-[2-[4-(2-甲基-5-喹啉基)-1-哌嗪基]乙基]苯基]-2-咪唑烷酮
- CBNumber:
- CB02627928
- 分子式:
- C25H29N5O
- 分子量:
- 415.53
- MOL File:
- 844903-58-8.mol
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GSK163090化学性质
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密度:
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1.216±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : 16.5 mg/mL (39.71 mM)
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形态:
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Solid
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酸度系数(pKa):
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14.20±0.20(Predicted)
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颜色:
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White to yellow
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GSK163090性质、用途与生产工艺
GSK163090 是一种有效的，选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4/8.5/9.7。GSK163090 抑制血清素再摄取转运蛋白 (SerT) 的功能活性，其 pKi 值为 6.1。GSK163090 具有抗抑郁和抗焦虑活性。
GSK163090
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上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2025/05/22 | HY-14348 | GSK163090
GSK163090 | 844903-58-8 | 1 mg | 373元 |
| 2025/05/22 | HY-14348 | GSK163090
GSK163090 | 844903-58-8 | 10mM * 1mLin DMSO | 844元 |
844903-58-8, GSK163090 相关搜索:
- 抑制剂
- C25H29N5O
- 化合物GSK163090,10 MM DMSO 溶液
- 化合物GSK163090
- 1-[3-[2-[4-(2-甲基-5-喹啉基)-1-哌嗪基]乙基]苯基]-2-咪唑烷酮
- 844903-58-8
- GSK163090, 10 mM in DMSO
- 1-(3-{2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl}phenyl)imidazolidin-2-one
- Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,anxiolytic,SerT,inhibit,5-HT1B,5-HT1D,5-HT Receptor,GSK-163090,GSK 163090,Serotonin Receptor,P-glycoprotein
- GSK163090 (GSK-163090
- CS-2298
- 5-HT1A/B/D receptor antagonist GS163090
- GSK163090; GSK-163090; GSK 163090.
- 2-Imidazolidinone,1-[3-[2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl]phenyl]-
- 1-[3-[2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl]phenyl]-2-imidazolidinone
- GSK163090