PLURISIN #2
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- CAS号:
- 56563-17-8
- 英文名:
- 1(2H)-Pyrimidinecarboxamide, 5-fluoro-3,4-dihydro-2,4-dioxo-N-phenyl-
- 英文别名:
- PluriSIn #2;1(2H)-Pyrimidinecarboxamide, 5-fluoro-3,4-dihydro-2,4-dioxo-N-phenyl-
- 中文名:
- PLURISIN #2
- 中文别名:
- CBNumber:
- CB28675514
- 分子式:
- C11H8FN3O3
- 分子量:
- 249.2
- MOL File:
- 56563-17-8.mol
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PLURISIN #2化学性质
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熔点:
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223 °C
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密度:
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1.51±0.1 g/cm3(Predicted)
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储存条件:
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4°C, protect from light, stored under nitrogen
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溶解度:
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DMSO: 5 mg/mL (20.06 mM)
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形态:
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Solid
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酸度系数(pKa):
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6.88±0.10(Predicted)
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颜色:
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White to off-white
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PLURISIN #2性质、用途与生产工艺
PluriSIn #2 是一种拓扑异构酶 II α (TOP2A) 的选择性转录抑制剂。PluriSIn #2 是一种选择性消除未分化的人类多能干细胞 (hPSC) 的化合物。
PluriSIn #2 (20 µM; 12 hours) treatment reduces TOP2A expression at the protein level.
A 24h exposure of PluriSIn #2 (20 µM) is sufficient to induce massive cell death in hPSCs, but doesn’t affect the viability of various other cell types derived from them.
Western Blot Analysis
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Cell Line:
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B153 and HUES9 human pluripotent stem cells (hPSCs)
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Concentration:
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20 µM
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Incubation Time:
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12 hours
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Result:
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Reduced TOP2A expression at the protein level.
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PLURISIN #2
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2025/05/22 | HY-111630 | PluriSIn #2 | 56563-17-8 | 1 mg | 1136元 |
| 2025/05/22 | HY-111630 | PluriSIn #2 | 56563-17-8 | 5mg | 2500元 |
56563-17-8, PLURISIN #2 相关搜索:
- 抑制剂
- 56563-17-8
- PluriSIn #2
- 1(2H)-Pyrimidinecarboxamide, 5-fluoro-3,4-dihydro-2,4-dioxo-N-phenyl-