N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
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- CAS号:
- 140926-75-6
- 英文名:
- NSC5844
- 英文别名:
- RE640;RE 640;RE-640;NSC5844;NSC5844 (RE640);NSC-5844 (NSC 5844;NSC 5844; NSC-5844; RE 640; RE-640; RE640;N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-;NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
- 中文名:
- N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
- 中文别名:
- 化合物 RE-640;化合物NSC5844;CCR1激动剂(NSC5844);N,N'-双(7-氯-4-喹啉)-1,2-乙二胺;N1,N2-双(7-氯喹啉-4-基)乙烷-1,2-二胺;NSC-5844 (NSC 5844;NSC5844;RE-640;RE 640;RE640)
- CBNumber:
- CB53121123
- 分子式:
- C20H16Cl2N4
- 分子量:
- 383.27
- MOL File:
- 140926-75-6.mol
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N,N'-双(7-氯-4-喹啉)-1,2-乙二胺化学性质
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沸点:
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632.6±55.0 °C(Predicted)
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密度:
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1.431±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMF: 0.33 mg/ml; DMSO: 0.25 mg/ml; Ethanol: slightly soluble
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形态:
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A crystalline solid
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酸度系数(pKa):
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6.61±0.50(Predicted)
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颜色:
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White to off-white
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N,N'-双(7-氯-4-喹啉)-1,2-乙二胺性质、用途与生产工艺
NSC5844 是 4-氨基喹啉衍生物，具有抗肿瘤和抗疟疾活性。
NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI
50
s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively. NSC5844 (Compound 1) is cytotoxic to
P. falciparum
, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of
P. falciparum
, with IC
50
s of 17 and 27 nM, respectively.
N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/05/22 | HY-100033 | N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
NSC5844 | 140926-75-6 | 1mg | 373元 |
| 2025/05/22 | HY-100033 | N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
NSC5844 | 140926-75-6 | 5mg | 1116元 |
N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
生产厂家
140926-75-6, N,N'-双(7-氯-4-喹啉)-1,2-乙二胺 相关搜索:
- 化学试剂
- 抑制剂
- 药靶配体
- 细胞生物学试剂
- NSC-5844 (NSC 5844;NSC5844;RE-640;RE 640;RE640)
- N1,N2-双(7-氯喹啉-4-基)乙烷-1,2-二胺
- 化合物 RE-640
- 化合物NSC5844
- CCR1激动剂(NSC5844)
- N,N'-双(7-氯-4-喹啉)-1,2-乙二胺
- 140926-75-6
- NSC-5844 (NSC 5844
- NSC 5844,RE640,NSC5844,inhibit,Inhibitor,RE 640,Parasite,NSC-5844
- 1,2-Ethanediamine, N1,N2-bis(7-chloro-4-quinolinyl)-
- N,N'-bis(7-chloroquinolin-4-yl)ethane-1,2-diamine
- NSC5844
- RE-640
- RE640
- RE 640
- NSC 5844; NSC-5844; RE 640; RE-640; RE640
- NSC5844 (RE640)