PTEN Polyclonal Antibody
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- CAS号:
- 英文名:
- ANTI-PTEN
- 英文别名:
- Anti-BZS;Anti-DEC;ANTI-PTEN;Anti-GLM2;Anti-MHAM;Anti-MMAC;ANTI-TEP-1;ANTI-MMAC1;Anti-PTEN1;PTEN (6H2.1)
- 中文名:
- PTEN Polyclonal Antibody
- 中文别名:
- CBNumber:
- CB5339655
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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PTEN Polyclonal Antibody化学性质
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储存条件:
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−20°C
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形态:
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buffered aqueous solution
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生物来源:
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rabbit
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PTEN Polyclonal Antibody性质、用途与生产工艺
该基因被鉴定为一种肿瘤抑制因子，在大量癌症中高频率突变。该基因编码的蛋白质是一种磷脂酰肌醇-3,4,5-三磷酸3-磷酸酶。它包含一个张力蛋白样结构域以及一个类似于双特异性蛋白酪氨酸磷酸酶的催化结构域。与大多数蛋白酪氨酸磷酸酶不同，该蛋白质优先对磷酸肌醇底物进行去磷酸化。它负向调节细胞内磷脂酰肌醇-3,4,5-三磷酸的水平，并通过负向调节AKT/PKB信号通路发挥肿瘤抑制作用。使用非经典（CUG）上游起始位点可产生更长的异构体，该异构体以亮氨酸起始翻译，并且被认为优先与线粒体内膜相关。这种较长的异构体可能有助于调节线粒体的能量代谢。该基因的一个假基因位于9号染色体上。可变剪接和多个翻译起始密码子的使用导致了编码不同异构体的多个转录变体。
PTEN Polyclonal Antibody
上下游产品信息
上游原料
下游产品
PTEN Polyclonal Antibody
生产厂家
PTEN Polyclonal Antibody 相关搜索:
- Tumor Suppressor Gene Products
- Tumor Growth Regulation
- PO to PYCancer Research
- PI3K-Akt-mTOR Pathway EnzymesAntibodies
- Primary Antibodies
- PO to PY
- PAntibodies
- Clone Index
- Cell Biology
- Antibodies to Lipids in Cell SignalingAntibodies
- Alphabetical Index
- Antibodies to Lipids in Cell SignalingCancer Research
- Anti-MMAC
- Anti-Phosphatase and tensin homolog
- Anti-DEC
- Anti-MGC11227
- Anti-MHAM
- Anti-BZS
- Anti-10q23del
- Anti-PTEN1
- Anti-phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
- Anti-GLM2
- PTEN (6H2.1)
- MONOCLONAL ANTI-PTEN
- ANTI-PHOSPHATASE AND TENSIN HOMOLOGY ON CHROMOSOME 10
- ANTI-PTEN, HUMAN
- ANTI-PTEN (188-403) SHEEP PAB
- ANTI-PTEN
- ANTISERUM TO PTEN
- ANTI-TEP-1
- ANTI-MMAC1
- Monoclonal Anti-PTEN antibody produced in mouse
- Anti-phospho-PTEN (pSer380/pThr382/pThr383) antibody produced in rabbit
- Anti-TP1 antibody produced in rabbit
- Anti-PTEN antibody produced in goat
- Anti-PTEN antibody produced in rabbit
- MONOCLONAL ANTIBODY TO PTEN
- PTEN POLYCLONAL ANTIBODY